Download

General topic

 

 

AJOPS | REVIEW ARTICLE
PUBLISHED: 30-09-2020

Review of the superficial circumflex iliac artery perforator flap: recommendations to the approach

Christopher Tam Song MD MRCS,1 Sandeep Bhogesha MD Fellow,1 Sharon Chu MD FRACS,1 Colin Song MD FAMS FRACS1


1 

Plastic Surgery Department
Fiona Stanley Hospital
Murdoch
Western Australia
AUSTRALIA

OPEN ACCESS
Correspondence
Name: Christopher Tam Song
Address: Fiona Stanley Hospital
11 Robin Warren Drive
Murdoch
Western Australia 6150
AUSTRALIA
Email: sanchezelsucia@gmail.com
Phone: +61 431 966 335
Citation: Song CT, Bhogesha S, Chu S, Song C. Review of the superficial circumflex iliac artery perforator flap: recommendations to the approach of a groin perforator flap. Australas J Plast Surg. 2020; 3(2):46–55.
DOI https://doi.org./10.34239/ajops.v3n2.193
Manuscript received: 05 January 2020
Manuscript accepted for review: 21 January 2020
Manuscript accepted: 03 March 2020
Copyright © 2020. Authors retain their copyright in the article. This is an open access article distributed under the Creative Commons Attribution Licence 4.0 which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.
Section: General reconstruction


Abstract

Introduction: The superficial circumflex iliac artery perforator (SCIP) flap has gained in popularity due to its thinness and superior donor site scar. However, there exist inconsistencies in the description of the surgical anatomy of the SCIP flap. The aim of this quantitative review was to provide a summary of published evidence to the surgical approach to such flaps.

Methodology: A literature review of the MEDLINE® and Cochrane databases was conducted. Articles were assessed by two reviewers using predefined data fields and selected using specific inclusion criteria. The two authors independently reviewed the literature and discrepancies were resolved by consensus.

Results: Included for evaluation were 39 articles. Of these, 30 fulfilled the criteria for surgical dissection, 16 for surgical anatomy and nine for preoperative imaging. The arterial anatomy of the groin perforator flap is variable and in 0.9 per cent of cases the pedicle originates from the superficial inferior epigastric artery rather than the superficial circumflex iliac artery (SCIA). The flap pedicle length is probably dependent on patient build and the course of the source vessel, rather than which groin perforator it is based on. CT is the gold standard preoperative imaging and should be used given the anatomical unpredictability. Lymphatics under the inguinal ligament and medial to the femoral artery should be preserved.

Conclusion: This quantitative study provides a guide to safe groin perforator flap harvest and surgical pearls to consider for surgical planning. An illustration is provided for ease of reference (Figure 3). The usage of this flap remains novel and further long-term outcomes have yet to be established.

Keywords: groin, perforator flap, iliac artery, microsurgery


Introduction

First described by Koshima in 2004,1 a classical superficial circumflex iliac artery perforator (SCIP) flap differs from a conventional groin flap in that it includes only a short distal segment of the superficial circumflex iliac artery (SCIA) system with a dominant perforator.

The SCIP flap has gained in popularity due to its thinness and superior donor site scar. The inguinal region is one of the thinnest areas of skin (dermis to epidermis: 625.9 to 273.4 μm in a Korean population) and is the ideal flap for soft-tissue defect reconstructions that are contour-essential.2 The scar of the SCIP flap is also well hidden within the underwear line. Like all perforator flaps, the SCIP flap can be customised to include different composition of tissues from skin, bone, subcutaneous fat, lymph nodes, vascularised nerve and fascia.3–9 The variations of the SCIP flap and their clinical applications have been well summarised by Iida and colleagues.10

There exist inconsistencies in the description of the surface location of the SCIA perforators and the attainable pedicle length for such flaps. The aim of this review was to provide a summary of published evidence regarding the surgical anatomy, preoperative imaging and surgical approach to safely identifying SCIP flaps.

Method

This study collates all publications on free SCIP flap reconstruction, with a particular focus on flap surgical anatomy, preoperative imaging and surgical approach to flap elevation. This review adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. This review and its authors also conform to the ethical principles of the Declaration of Helsinki of the World Medical Association.

The literature search was performed by two independent reviewers through the MEDLINE® and Cochrane databases. The Medical Subject Headings search terms included ‘superficial circumflex iliac perforator’, ‘SCIP’ and ‘groin perforator’. A free text search or a Medical Subject Headings term search was used wherever appropriate, and Boolean operators were used to combine the terms. There were no restrictions on publication date or status.

Eligibility criteria

The inclusion criteria consisted of any meta-analyses, systematic reviews, case-control and cohort studies, or case reports involving SCIP flap surgical anatomy, preoperative imaging and surgical dissection. Articles excluded for surgical anatomy were those that involved paediatric patients, flaps raised without a cutaneous component and studies that did not include flap pedicle dimensions. Chimeric flaps were also excluded from the study.

Study selection and data collection process

Citations found by means of searching the databases were screened for eligibility by title and/or abstract. Full-text articles were then appraised for final inclusion in the quantitative analysis. The two reviewers listed extracted data separately, and discrepancies were reviewed and discussed until a consensus was accomplished.

Results and discussion

Through the initial search, 189 articles were identified (Figure 1). After screening the titles, 76 publications remained. This number was further reduced to 39 articles after reading the abstracts. Of these 39 articles (not mutually exclusive), 30 fulfilled the criteria for surgical dissection, 16 for surgical anatomy and nine for preoperative imaging. A total of 587 dissections were evaluated for the results of this study.

Song-Fig-1

Fig 1. Flow diagram of the search and selection strategy for included articles.

Groin perforator flap surgical anatomy

We summarised the literature on SCIP flap surgical anatomy and studies identified from the literature search were included if they described information on perforator origin, pedicle length, arterial diameter, flap size and thickness, and vein harvested for anastomosis.

There are multiple blood supplies in the groin region, with contributions from the SCIA, superficial inferior epigastric artery (SIEA), fourth lumbar artery, deep circumflex iliac artery and superior gluteal artery systems.11 For the purpose of relevance to this review, only the anatomy of the SCIA and SIEA are described. The course of the SCIA remains variable. Taking advantage of the advent of preoperative computed tomography angiography (CTA), Suh conducted the largest study of SCIA anatomy.12 Of 284 SCIA in 142 patients, most originated from the femoral artery (83.5%), while some originated from the superficial femoral artery (8.5%) or deep circumflex femoral artery (7%) and only a few (1%) originated from the lateral circumflex femoral artery. There also remains variability as to the origin of the SIEA. In 38 dissections, the origin of the individual SIEA arose directly from the common femoral artery (CFA), a common trunk with the SCIA, a common trunk with the pudendal artery and the superficial femoral artery in 22 (57.9%), seven (18.4%), two (5.3%) and five (13.2%) of 38 dissections, respectively. In the remaining two cases, the SIEA originated from the external iliac artery or the lateral circumflex femoral branch of the deep femoral artery.13

In relation to the SIEA, the SCIA was described as sharing a common origin in 48 per cent of cases, as a large SCIA without a SIEA in 35 per cent of cases and both a SCIA and a SIEA with separate origins in 17 per cent of cases.11

In some instances, groin perforators can be supplied by the SIEA system rather than the SCIA system.14–16 The anatomical variation encountered during this systematic review could not be explained better by Pan’s study of angiosomes in the thigh and buttock, which found that the origin of the source arteries and their branches was subject to considerable variation, while the area of skin supplied by each cutaneous perforator was relatively constant.17 Therefore, the terminology ‘groin perforator flap’ is more appropriate than ‘SCIP flap’.

Figure 2 illustrates the two variations of the groin perforator flap when basing it on either the medial or lateral perforator. In most cases, the medial perforator of the groin arises about 1.5cm distal to the SCIA origin from the femoral artery. In Suh’s study, it originated from the SCIA in 134 of 142 (94.4%) patients, the SIEA in five (3.5%) patients, the superficial femoral artery in two (1.4%) and the superficial pudendal artery in one (0.7%).18 It then penetrates the deep and superficial fascia directly after it branches from the SCIA.18,19 The lateral perforator follows a musculocutaneous course superolaterally beneath the deep fascia, parallel to the inguinal ligament. It then pierces the Sartorius muscle medially and perforates the deep fascia at its lateral border.1,19–21

Song-fig-2

Fig 2. Illustration demonstrating the differences in groin perforator flap harvest. The left half of the flap is based on the medial perforator while the right half is based on the lateral perforator. Note the greater deep fascial violation and intra-muscular dissection for the lateral perforator. In addition, the lateral femoral cutaneous nerve runs in close proximity and should be preserved. Illustration by Kaye Lirio, medical graphic designer, medical illustrations department, Fiona Stanley Hospital, Murdoch, Western Australia.

Table 1 summarises the variability in the literature regarding the description of the surface location of either the medial or lateral groin perforators.1,10,14,15,22–25 It can therefore be challenging to suggest precise anatomical landmarks for the perforators. However, what remains consistent is that the lateral perforator lies directly above the Sartorius muscle in the groin region, while the medial perforator lies in close proximity to the inguinal ligament and is medial to the Sartorius muscle. This accentuates the value of CTA as it aids preoperative perforator marking with a Doppler probe.

Table 1: Various studies describing the anatomical location of both the medial and lateral groin perforator
Groin perforator location
No. Study Medial Lateral
1 Salmon, 193622 Medial border of Sartorius muscle
2 Koshima, 20041 3cm medial to ASIS
3 Sinna, 201023 Through Sartorius muscle
4 Iida, 201410 1cm medial to ASIS
5 Ma, 201624 2–3cm medial to ASIS 1.5–2cm inferior to ASIS
6 Yoshimatsu, 201615 Medial edge of Sartorius muscle
7 Feng, 201714 Midpoint of inguinal ligament 2–3cm medial to ASIS
8 Lee, 201725 2–4cm below inguinal ligament, 2–5cm lateral to femoral vessels  –

ASIS=anterior superior iliac spine.

Groin perforator flap anatomy and outcomes

A total of 584 flaps from 16 studies were included in this anatomical systematic review of SCIP flaps (Table 2).14,15,19,23–32,33–35 Of these, 579 (99.1%) were based on the SCIA while five were based on the SIEA (0.9%). The arterial diameters ranged from 0.3 mm to 1.8 mm, flap size from 2 cm to 224cm2 and flap thickness from 3 mm to 23 mm. Medial perforator flap pedicle length ranged from 20 mm to 90 mm. For lateral perforator flaps the range of pedicle length was 26 mm to 100 mm (where 100 mm was achieved when based on reverse flow via the transverse branch of the lateral branch of the SCIA).14

Multiple studies describe achieving a longer pedicle length by dissecting the lateral perforator. However, the results displayed in Table 2 are inconsistent with this: Jin reported a 69 mm (range 48–90 mm) pedicle length for a medial perforator flap when dissected down to the SCIA origin.34 In contrast, Feng reported a mean length of 59 mm (range 26–100 mm) for lateral perforator flaps that were ligated at the SCIA origin.14 In fact, patient build and variability in groin arterial anatomy may be the determining factors for absolute pedicle length.

Table 2: Studies with various groin perforator flap and pedicle dimensions and differences when based on either the medial or lateral perforator
SCIA perforator Pedicle length Arterial diameter Flap size Flap thickness
No. Study Flaps, n Medial Lateral Others Mean (range), mm Mean (range), mm Mean (range), mm Mean (range), mm Proximal pedicle ligation
1 Hsu, 200719 12 100 1 – (–) 0.5–2 (–) SCIA origin
2 Sinna, 201023 20 20 48 (30–80) 0.85 (0.7–1) 162 (75–375) – (–) SCIA origin
3 Song 201226 10 10 45 (–) 0.7 (–) 105 (–) 5 (–) Not specified
4 Hong, 201327 79 53 26 50 (25–70) 0.7 (0.4–1.2) 75.7 (17.5–175) 0.5 (0.3–1.2) Deep fascia
5 Green, 201328 4 4 10 20 (–) SCIA origin
6 Iida, 201429 12 71 (60–90) – (–) 80.6 (8–144) – (–) Branch origin
7 Goh, 201430 210 193 17 50 (25–70) 0.7 (0.4–1.2) 86.3 (–) 0.5 (0.3–1.2) Not specified
8 Yoshimatsu, 201531 1 1 120 (–) 0.8 (–) – (–) – (–) Reverse arterial flow based on transverse branch of deep branch
9 Jin, 201532 6 6 69 (48–90) 0.6 (0.5–0.7) – (–) – (–) SCIA origin
10 Kim, 201533 55 41 11 45 (25–55) 0.7 (0.5–1) 75 (24–140) 0.3–0.8 (0.5) Not specified
11 Ma, 201624 9 9 87 (65–90) 0.8 (0.5–1.2) 40.6 (35–45) – (–) SCIA origin
12 He, 201634 15 79 (–) 0.7 (–) 83 1.2 (0.7–1.5) SCIA origin
13 Yoshimatsu, 201615 27 24 7 60 (20–100) 1 (0.5–2.0) 59 (2–224) – (–) Not specified
14 Narushima, 201635 6 5 45 (20–70) 0.7 (0.7–0.8) 49.5 (16–84) 0.2 (0.2) Not specified
1 SIEA – (–) 1 (–) 20 (–) 0.25 (–)
15 Feng, 201714 80 51 43 (26–62) 0.2 – (–) 0.7 (0.5–1.2) SCIA origin (length up to 10cm with reverse arterial flow based on deep branch in one case)
25 59 (26–100) 0.3 – (–) 1.5 (0.8–2.3)
4 SIEA – (–) – (–) – (–) – (–)
16 Lee, 201727 41 41 45 (45–70) 0.84 (0.4–1.8) 16.2 (5–31.5) – (1.5–4) Branch origin

All but two of the 16 studies reported flap outcomes.23,35 From a total of 554 flaps, 520 had complete flap survival (93.3%), 20 had partial necrosis (3.6%) and 14 were a total loss (2.5%). Donor site morbidity was reported by two studies with a total of three cases of complication (0.5%). Goh and colleagues performed 210 flaps and reported one case each of donor site-related seroma and lymphorrhoea,30 while Lee and colleagues performed 41 flaps and reported one case of donor site seroma postoperatively.25

Flap venous anastomosis

Table 3 depicts seven studies with a description of their venous anastomoses for groin perforator flaps based on the SCIA.14,23,24,30,31,33,35 In comparison with the arterial anatomy, there remains a relative scarcity in the anatomical description of the venous system of the SCIP flap. Of 407 flaps, 132 (32.4%) venae comitantes (VC) and 251 (61.7%) superficial circumflex iliac veins (SCIV) were used for venous anastomosis. Goh concluded that in a series of 210 SCIP flaps, the flap outcomes of single (144) and dual venous anastomosis (66) were no different (4.5% and 4.9% flap success, respectively).30

Table 3: A summary of the studies on venous anastomosis to either the pedicle venae comitantes (VC) or superficial circumflex iliac vein (SCIV)
Medial perforator VC anastomosis Lateral perforator VC anastomosis SCIV anastomosis
No. Study Flaps, n Anastomosis to VC, n  n Diameter average (range), mm  n Diameter average (range), mm  n Diameter average (range), mm
1 Sinna, 201023 20 20 0 0.73 0.73 (0.6–1.0) 0
2 Goh, 201430 210 90 120
3 Feng 201514 80 7 73
4 Ma, 201524 9 9 9 1.1 (0.8–1.4) 0 0
5 Kim, 201533 55 0 55 >1.2
6 Yoshimatsu, 201615 27 0.9 (0.3–1.5) 0.5 (0.4–1.2) 2.0 (1.0–3.0)
7 Narushima, 201635 6 6 5 1 (0.5–1.5) 0 3 2.2 (2.0–2.5)

Preoperative imaging

As discussed above, variability in the course of the source arteries (SCIA/ SIEA) and the groin perforators justifies a preoperative CTA. This confers easier flap dissection and can aid in Doppler ultrasound preoperative marking. CTA (augmented with multi-detector rows) provides useful three-dimensional mapping of the SCIA and vessel calibre. It identifies the course and branching pattern of the SCIA, which is important for flap design, decreasing the harvest time and improving the
safety of the flap.34 A systematic review of perforator flap preoperative imaging concluded that CTA is the gold standard in terms of accuracy, reproducibility and lower inter-operator variability.36 With the utility of CTA, this negates the unpredictability of the dominant perforator of the flap and the need to change flap design based on intraoperative findings. However, tracing of the perforators becomes challenging if the subcutaneous adipose layer is very thin or in the presence of a haematoma collection.12,37 In obese patients where anatomical landmarks cannot be accurately located, CTA can been used to radiologically pin-point where the perforators pierce the superficial and deep fascias. This is important in such instances, as excess adipose tissue can make perforator dissection challenging. A technique using the umbilical button as a reference point to mark the critical points where the perforator penetrates both fascias in CTA has been described.38

The Doppler probe is a fast, non-invasive and portable preoperative tool that remains crucial for surface markings of perforators of interest and can be quickly guided by CTA. Duplex ultrasound remains inferior to CTA in three-dimensional mapping and is operator dependent. However, it does provide information on vessel calibre and flow velocity, although it may become less useful with vessel diameters smaller than 0.5 mm.39 It has been shown to be able to detect hypoplasia in the SCIA/SIEA network and therefore can be beneficial in locating the source artery of the groin perforator, especially when CTA fails to do so in patients with a paucity of subcutaneous fat.

Surgical dissection

The limitation of a short pedicle in Koshima’s original description of the SCIP flap can be overcome by including the entire length of the SCIA. This has the dual effect of increasing vessel diameter size and pedicle length.28 There is also the option of pedicle elongation through reverse arterial flow from the distal deep end of the lateral SCIA branch and selecting the medial groin perforator (if anatomically supplied by the superficial branch).14,31

Inferolateral dissection of the SCIP flap remains a popular approach with right-handed surgeons due patient positioning and it also aids easy identification of Scarpa’s fascia over the anterior superior iliac spine (ASIS) due to the loose subcutaneous areolar connective tissue. However, novice surgeons may miss the medial perforator (supra-Scarpa’s fascia course) after dissecting out the lateral perforator (sub-Scarpa’s fascia course) and a superomedial approach would be safer. This becomes even more challenging in skinny patients with thin fat planes. In general, the flaps are elevated in the suprafascial plane to avoid the need for flap debulking. This plane can be identified by the difference in fat lobule sizes as they are smaller superficially and larger in the deeper plane.40,41

Earlier SCIP anatomical studies reported that the SCIA medial branch at times was hypoplastic or absent.1,19 However, Suh’s study demonstrated its ubiquity in the SCIA system on CTA.12 The finding that the branch appears hypoplastic intraoperatively may in part be due to the vasospasm that occurs during surgical dissection. In addition, as mentioned above, a deep and lateral approach to flap dissection may fail to identify the course of the vessel due to its medial and supra-Scarpa’s fascia course. A medial dissection approach, in addition, may keep the lateral perforator preserved should a bail-out option be required if the medial perforator is damaged iatrogenically.15 As such, there are no long-term data yet to recommend one approach over the other. Therefore, while bearing in mind the key advantages of each approach, the microsurgeon’s comfort with either technique should take precedence. A comprehensive video illustration has been included in a previous paper.30

For the lateral groin perforator, attention must be given to the lateral cutaneous nerve of the thigh, which transverses the branch anteriorly, after the vessel travels along the lateral border of the Sartorius muscle.11

Evaluation of the risk of lymphoedema

The risk of iatrogenic lower limb lymphoedema is difficult to quantify due to the paucity of cases reported. It is also confounded by the possible existence of a genetic predisposition to secondary lymphoedema.42 Vignes and colleagues reported two patients (out of 26) suffering from lower limb iatrogenic lymphoedema after inguinal lymph node harvest.43 However, no information was provided about which group and the number lymph nodes that were harvested. A case report saw ipsilateral leg lymphoedema as a complication when harvesting a lymph node-SCIP flap based on the medial branch.44

Sentinel lymph nodes in the superficial groin are mostly located at the saphenofemoral junction and the quadrant inferomedial to this (78%).45 A study that evaluated donor site lymphatic function changes after lymph node harvest in the groin recommended avoiding the lymph nodes and lymphatic vessels located under the inguinal ligament and medial to the femoral artery, and that unnecessary surgical trauma in this area should be avoided.46 Another study, in an attempt to preserve the superficial inguinal nodes, harvested lymphatic vessels from the abdomen for a chimeric SCIP flap.7 It has also been suggested that preoperative indocyanine green (ICG) lymphography could be used to identify dominant lymph nodes that should be preserved during lymph node transfer.47

Limitations

There were limitations of the SCIP flap anatomical review. In some instances, information that was not available included whether the flap was based on medial or lateral perforators, and whether pedicle dissection was down to the SCIA origin or just to the branch origin. Ideally a formal statistical analysis comparing the success rates of medial and lateral groin perforator flaps should be undertaken, but there was insufficient detail in the relevant studies to do so. In addition, heterogeneity in flap design and variability, and small study numbers precluded any meaningful qualitative analysis. Also lacking was a description and the outcomes of venous anastomosis, which would have been useful to evaluate postoperative flap congestion. Long-term outcomes of SCIP flap utilisation in the various reconstructive fields have yet to be established.

Groin perforator flap literature review summary

Based on the results of this systematic review, we have devised a step-wise summary (Figure 3) to the dissection of a groin perforator flap.

Song-fig-3

Fig 3. A step-wise approach to safe groin perforator flap harvest

Conclusion

Distinct advantages for the free groin perforator flap include its thinness and concealed donor site scar. However, there remain concerns about a short pedicle length and variability in perforator anatomy. This quantitative review provides an algorithm that may grant safer flap harvest by providing strategic preoperative steps to negate the shortcomings of a potentially useful flap.

Disclosure

The authors have no financial or commercial conflicts of interest to disclose.

Acknowledgements

Thanks to Kaye Lirio, Medical Graphic Designer Medical Illustrations Department, Fiona Stanley Hospital, Murdoch, Western Australia for Figure 2.

References

  1. Koshima I, Nanba Y, Tsutsui T, Takahashi Y, Urushibara K, Inagawa K, Hamasaki T, Moriguchi T. Superficial circumflex iliac artery perforator flap for reconstruction of limb defects. Plast Reconstr Surg. 2004;113(1):233–40. https://doi.org/10.1097/01.PRS.0000095948.03605.20
  2. Y Lee, K Hwang. Skin thickness of Korean adults. Surg Radiol Anat. 2002;24(3–4):183–89. https://doi.org/10.1007/s00276-002-0034-5
  3. Yamamoto T, Saito T, Ishiura R, Iida T. Quadruple-component superficial circumflex iliac artery perforator (SCIP) flap: a chimeric SCIP flap for complex ankle reconstruction of an exposed artificial joint after total ankle arthroplasty. J Plast Reconstr Aesthetic Surg. 2016;69(9):1260–265. https://doi.org/10.1016/j.bjps.2016.06.010
  4. Pan Z, Jiang P, Xue S, Liu X, Zhao Y, Li H. Free vascularised osteocutaneous flap based on superficial circumflex iliac vessel transfer for the reconstruction of limb defects. J Plast Reconstr Aesthetic Surg. 2013;66(5):e152–54. https://doi.org/10.1016/j.bjps.2013.01.017
  5. Iida T, Narushima M, Yoshimatsu H, Yamamoto T, Araki J, Koshima I. A free vascularised iliac bone flap based on superficial circumflex iliac perforators for head and neck reconstruction. J Plast Reconstr Aesthetic Surg. 2013;66(11):1596–599. https://doi.org/10.1016/j.bjps.2013.03.031
  6. Kashiwa K, Kobayashi S, Nasu W, Kuroda T, Higuchi H. Facial nerve reconstruction using a vascularized lateral femoral cutaneous nerve graft based on the superficial circumflex iliac artery system: an application of the inferolateral extension of the groin flap. J Reconstr Microsurg. 2010;26(09):577–82. https://doi.org/10.1055/s-0030-1263288
  7. Mihara M, Tange S, Hara H, Han Peng Z, Haragi M, Muarai N. Modified lymph vessel flap transplantation for the treatment of refractory lymphedema: a case report. Microsurg. 2016;36(8):695–99. https://doi.org/10.1002/micr.22402
  8. Akita S, Mitsukawa N, Kubota Y, Sakakibara M, Nagashima T, Satoh K. Delayed partial breast reconstruction and vascularized lymph node transfer by a superficial circumflex iliac artery perforator flap. Plast Reconstr Surg. 2016;137(2):490e–91e. https://doi.org/10.1097/PRS.0000000000002112
  9. Koshima I, Nanba Y, Tsutsui T, Itoh S. Sequential vascularized iliac bone graft and a superficial circumflex iliac artery perforator flap with a single source vessel for established mandibular defects. Plast Reconstr Surg. 2004;113(1):101–06. https://doi.org/10.1097/01.PRS.0000090725.89401.DE
  10. Iida T. Superficial circumflex iliac perforator (SCIP) flap: variations of the SCIP flap and their clinical applications. J Reconstr Microsurg. 2014;30(07):505–08. https://doi.org/10.1055/s-0034-1370360
  11. Strauch B, Yu H-L. Atlas of microvascular surgery. 2nd ed. Thieme; 2006. [cited 27 May 2017.] Available from: http://www.thieme.com/books-main/plastic-surgery/product/631-atlas-of-microvascular-surgery
  12. Suh HSP, Jeong HH, Choi DH, Hong JPJP. Study of the medial superficial perforator of the superficial circumflex iliac artery perforator flap using computed tomographic angiography and surgical anatomy in 142 patients. Plast Reconstr Surg. 2017;139(3):738–48. https://doi.org/10.1097/PRS.0000000000003147
  13. Fathi M, Hatamipour E, Fathi HR, Abbasi A. The anatomy of superficial inferior epigastric artery flap. Acta Cir Bras. 2008;23(5):429–34. https://doi.org/10.1590/S0102-86502008000500007
  14. Feng S, Xi W, Zhang Z, Tremp M, Schaefer DJ, Sadigh PL, Zhang W, Zhang YX. A reappraisal of the surgical planning of the superficial circumflex iliac artery perforator flap. J Plast Reconstr Aesthetic Surg. 2017;70(4):469–77. https://doi.org/10.1016/j.bjps.2016.11.025
  15. Yoshimatsu H, Yamamoto T, Hayashi A, Iida T. Proximal-to-distally elevated superficial circumflex iliac artery perforator flap enabling hybrid reconstruction. Plast Reconstr Surg. 2016;138(4):910–22. https://doi.org/10.1097/PRS.0000000000002607
  16. Harii K, Ohmori K, Torii S, Murakami F, Kasai Y. Free groin skin flaps. Br J Plast Surg. 1975;28(4):225–37. https://doi.org/10.1016/0007-1226(75)90022-3
  17. Pan WR, Taylor GI. The angiosomes of the thigh and buttock. Plast Reconstr Surg. 2009;123(1):236–49. https://doi.org/10.1097/PRS.0b013e3181934873
  18. Suh HS, Jeong HH, Hong JP. Study of the medial superficial perforator of the superficial circumflex iliac artery perforator flap using CT angiography and surgical anatomy in 142 patients. Plast Reconstr Surg. 2017;139(3):738–748. https://doi.org/10.1097/PRS.0000000000003147
  19. Hsu WM, Chao WN, Yang C, Fang CL, Huang KF, Lin YS, Lee TH. Evolution of the free groin flap: the superficial circumflex iliac artery perforator flap. Plast Reconstr Surg. 2007;119(5):1491–498. https://doi.org/10.1097/01.prs.0000256057.42415.73
  20. He Y, Tian Z, Ma C, Zhang C. Superficial circumflex iliac artery perforator flap: identification of the perforator by computed tomography angiography and reconstruction of a complex lower lip defect. Int J Oral Maxillofac Surg. 2015;44(4):419–23. https://doi.org/10.1016/j.ijom.2014.11.001
  21. Gentileschi S, Servillo M, De Bonis F, Albanese R, Pino V, Mangialardi ML, Valente I, Garganese G, Scambia G, Salgarello M, Cina A. Radioanatomical study of the pedicle of the superficial circumflex iliac perforator flap. J Reconstr Microsurg. 2019;35(9):669–76. https://doi.org/10.1055/s-0039-1693144
  22. Salmon M. Artères de la peau. Paris: Masson, 1936.
  23. Sinna R, Hajji H, Qassemyar Q, Perignon D, Benhaim T, Havet E. Anatomical background of the perforator flap based on the deep branch of the superficial circumflex iliac artery (SCIP flap): a cadaveric study. Eplasty. 2010;10:e11
  24. Ma C, Tian Z, Kalfarentzos E, Zhang Y, Zhang Z, Lam D, Zhang C, He Y. Superficial circumflex iliac artery perforator flap for tongue reconstruction. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;121(4):373–80. https://doi.org/10.1016/j.oooo.2015.10.034
  25. Lee K-T, Park BY, Kim E-J, Kim J-H, Jang K-T, Choi S-H, Lee D-Y, Mun G-H. Superthin SCIP flap for reconstruction of subungual melanoma. Plast Reconstr Surg. 2017;140(6):1278–289. https://doi.org/10.1097/PRS.0000000000003881
  26. Song J, Ben-Nakhi M, Hong J. Reconstruction of lower extremity with perforator free flaps by free style approach in pediatric patients. J Reconstr Microsurg. 2012;28(09):589–94. https://doi.org/10.1055/s-0032-1315785
  27. Hong JP, Sun SH, Ben-Nakhi M. Modified superficial circumflex iliac artery perforator flap and supermicrosurgery technique for lower extremity reconstruction. Ann Plast Surg. 2013;71(4):380–83. https://doi.org/10.1097/SAP.0b013e3182503ac5
  28. Green R, Rahman KMA, Owen S, Paleri V, Adams J, Ahmed OA, Ragbir M. The superficial circumflex iliac artery perforator flap in intra-oral reconstruction. J Plast Reconstr Aesthetic Surg. 2013;66(12):1683–687. https://doi.org/10.1016/j.bjps.2013.07.011
  29. Iida T, Mihara M, Yoshimatsu H, Narushima M, Koshima I. Versatility of the superficial circumflex iliac artery perforator flap in head and neck reconstruction. Ann Plast Surg. 2014;72(3):332–36. https://doi.org/10.1097/SAP.0b013e318260a3ad
  30. Goh TLH, Park SW, Cho JY, Choi JW, Hong JP. The search for the ideal thin skin flap. Plast Reconstr Surg. 2015;135(2):592–601. https://doi.org/10.1097/PRS.0000000000000951
  31. Yoshimatsu H, Yamamoto T, Iida T. Pedicle elongation technique of superficial circumflex iliac artery perforator flap. J Plast Reconstr Aesthetic Surg. 2015;68(3):e61–62. https://doi.org/10.1016/j.bjps.2014.11.018
  32. Jin S, He Y, Tian Z, Feng S, Zhang Y. Superficial circumflex iliac artery perforator flap aided by color Doppler sonography mapping for like-with-like buccal reconstruction. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;119(2):170–76. https://doi.org/10.1016/j.oooo.2014.10.024
  33. Kim J, Kim K, Yoon C. Reconstruction of moderate-sized distal limb defects using a superthin superficial circumflex iliac artery perforator flap. J Reconstr Microsurg. 2015;31(9):631–35. https://doi.org/10.1055/s-0035-1558959
  34. He Y, Jin S, Tian Z, Fang Z, Ma C, Tao X, Zhang Y, Qiu W, Zhang Z, Zhang C. Superficial circumflex iliac artery perforator flap’s imaging, anatomy and clinical applications in oral maxillofacial reconstruction. J Cranio-Maxillofac Surg. 2016;44(3):242–48. https://doi.org/10.1016/j.jcms.2015.12.002
  35. Narushima M, Iida T, Kaji N, Yamamoto T, Yoshimatsu H, Hara H, Kikuchi K, Araki J, Yamashita S, Koshima I. Superficial circumflex iliac artery pure skin perforator-based superthin flap for hand and finger reconstruction. J Plast Reconstr Aesthetic Surg. 2016;69(6):827–34. https://doi.org/10.1016/j.bjps.2016.03.005
  36. Pratt GF, Rozen WM, Chubb D, Ashton MW, Alonso-Burgos A, Whitaker IS. Preoperative imaging for perforator flaps in reconstructive surgery. Ann Plast Surg. 2012;69(1):3–9. https://doi.org/10.1097/SPA.0b013e318222b7b7
  37. Hong JP. The use of supermicrosurgery in lower extremity reconstruction: the next step in evolution. Plast Reconstr Surg. 2009;123(1):230–35. https://doi.org/10.1097/PRS.0b013e3181904dc4
  38. Pereira N, Parada L, Kufeke M, Troncoso E, Roa R. A new planning method to easily harvest the superficial circumflex iliac artery perforator flap. J Reconstr Microsurg. 2020;36(3):165–70. https://doi.org/10.1055/s-0039-1698444
  39. Su W, Lu L, Lazzeri D, Zhang YX, Wang D, Innocenti M, Qian Y, Agostini T, Levin LS, Messmer C. Contrast-enhanced ultrasound combined with three-dimensional reconstruction in preoperative perforator flap planning. Plast Reconstr Surg. 2013;131(1):80–93. https://doi.org/10.1097/PRS.0b013e3182729e9e
  40. Hong J, Choi D, Suh H, Mukarramah DA, Tashti T, Lee K, Yoon C. A new plane of elevation: the superficial fascial plane for perforator flap elevation. J Reconstr Microsurg. 2014;30(07):491–96. https://doi.org/10.1055/s-0034-1369807
  41. Berner JE, Nikkhah D, Zhao J, Prousskaia E, Teo TC. The versatility of the superficial circumflex iliac artery perforator flap: a single surgeon’s 16-year experience for limb reconstruction and a systematic review. J Reconstr Microsurg. 2020;36(2):93–103. https://doi.org/10.1055/s-0039-1695051
  42. Newman B, Lose F, Kedda MA, Francois M, Ferguson K, Janda M, Yates P, Spurdle AB, Hayes SC. Possible genetic predisposition to lymphedema after breast cancer. Lymphat Res Biol. 2012;10(1):2–13. https://doi.org/10.1089/lrb.2011.0024
  43. Vignes S, Blanchard M, Yannoutsos A, Arrault M. Complications of autologous lymph-node transplantation for limb lymphoedema. Eur J Vasc Endovasc Surg. 2013;45(5):516–20. https://doi.org/10.1016/j.ejvs.2012.11.026
  44. Sun W, Fang J, Yong Q, Li S, Xie Q, Yin J, Cui L. Subcutaneous construction of engineered adipose tissue with fat lobule-like structure using injectable poly-benzyl-l-glutamate microspheres loaded with adipose-derived stem cells. PLoS One. 2015;10(8):e0135611. https://doi.org/10.1371/journal.pone.0135611
  45. van der Ploeg IMC, Kroon BBR, Valdés Olmos RA, Nieweg OE. Evaluation of lymphatic drainage patterns to the groin and implications for the extent of groin dissection in melanoma patients. Ann Surg Oncol. 2009;16(11):2994–999. https://doi.org/10.1245/s10434-009-0650-y
  46. Viitanen TP, Mäki MT, Seppänen MP, Suominen EA, Saaristo AM. Donor-site lymphatic function after microvascular lymph node transfer. Plast Reconstr Surg. 2012;130(6):1246–253. https://doi.org/10.1097/PRS.0b013e31826d1682
  47. Mihara M, Iida T, Hara H, Hayashi Y, Yamamoto T, Narushima M, Hayami S, Sawamoto N, Naito M, Koshima I. Autologous groin lymph node transfer for ‘sentinel lymph network’ reconstruction after head-and-neck cancer resection and neck lymph node dissection: a case report. Microsurg. 2012;32(2):153–57. https://doi.org/10.1002/micr.20970